xxx. I used Clariton (over the counter) to combat the bone aches from chemo and the injection. Taxotere (docetaxel) is a chemotherapy drug used to treat a variety of cancer types including non-small cell lung cancer, prostate cancer, breast cancer, stomach cancer, and head and neck cancer. Musculoskeletal manifestations usually are transient, occurring within a few days after docetaxel administration lasting about 4 days. It really helped me that there was a gap between the two sets of chemo cycles, gave me a chance to recover a bit from the taxotere before starting the treatments again. There is a risk that this medication may leak out of the vein at the injection site, resulting in tissue damage that can be severe. They didnt feel great, but it wasnt bad. Progression-free survival was 2-3 months for both groups. At least week three is getting close, mine starts next Tuesday. There are a number of things you can do to manage the side effects of docetaxel. Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them. Doreen D. (Breast Cancer, Invasive Ductal Carcinoma, Stage 2A,Triple Positive). I'm on my 6th Dox this week, (last one) and I mentioned to my oncologist on 3rd dose that i was awake ALL night on the steroids - I had been prescribed 8mg Dexamethasone twice daily starting day before and finishing on day after Dox. Furthermore, the overall response rate for docetaxel in the intent-to-treat population (42.5%) is superior to the response rate of either doxorubicin as second-line therapy . 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I did start taking codeine and paracetamol but that caused severe constipation and bowel issues. All rights reserved. Your fingernails/toenails may become dark, brittle or fall off. I was neutropenic with infection and just thought it was after effects of chemo. So I am sorry to confirm what you already know - the Taxotere is s*** and much more agressive than the FEC but you will get to the end of it. Docetaxel interferes with the function of microtubules, resulting in inactive microtubule bundles, causing cells to die. Hope you are all enjoying the sunshine and feeling better. Pineapple is good for helping the nasty taste and I know someone who sucked frozen pineapple cubes and this helped her a lot. One of the common types of chemotherapies for breast cancer, AC + T includes three drugs: doxorubicin (Adriamycin), cyclophosphamide (Cytoxan), and a taxane drug (Taxol, Taxotere . Drink 8-10 glasses of non-alcoholic, un-caffeinated fluid a day to prevent dehydration. I think it would have been better to know just what to expect but as we all react different it's not possible. I was informed that I would need a mastectomy as to the way the tumour is growing in the breast. For obvious reasons, Saturday is the best day of the week because it's a holiday and the next day too is a holiday, followed by Friday because it's preceded by two holidays. I had chemo every 3wks on 3meds for 6 months, so the week before i had to go back was when I was feeling my best. It won't be long until you to are in a position to help others with your experiences of the journey we all find ourselves on. I am just unfortunate to get them all. Your Wife is unique! as these can all increase the risk of bleeding. Shari S. (Breast Cancer, Invasive Ductal Carcinoma (IDC),Triple Positive, Stage 4). Try saltines, or ginger ale to lessen symptoms. Nutrition is an important part of your care. Sounds like you have had quite a week, similar to mine. xx, My consultant reduced my injection strength so I had to endure 10 injections as prescribed. If you are not eating enough, nutritional supplements may help. You may experience a metallic taste or find that food has no taste at all. You may also experience difficulty breathing, joint stiffness, pain, and even behavioral changes. Some common Taxotere side effects include: Heres what cancer patients had to say about their experiences with Taxotere: I started chemotherapy. Week Three was Im actually feeling pretty good and then you go right back to Week One. Do not floss or use toothpicks and use a soft-bristle toothbrush to brush your teeth. Taxotere is a mitotic inhibitor that interferes with your bodys cell division process. Chemotherapy kills regular cells, as well as cancer cells, and this is why side effects occur . These Taxotere side effects are less common, meaning they occur in 10-29 percent of patients receiving Taxotere: Vomiting Muscle/bone/joint pain (myalgias and arthralgias) Low platelet count (This can increase your risk of bleeding) Increases in blood tests measuring liver function. Alternative therapies can help for relaxation althrough at th emoment i go for the glass of wine cure. The ninth-largest drop was . In some ways was easier, in others was more taxing (pun intended)! TC ( Taxotere and cyclophosphamide) is a common chemotherapy regimen given for localized breast cancers that require chemotherapy. It had to have been that I just did too much. Liked the clearer head but found days 3 to 6 the worst when ankles, knees or hips gave way. If you ask about people's favourite CPAP machine, you can find those who love an APAP instead. 10 year old is self sufficient. I followed all the advice and recommendations given by the medical team and tried to be positive about the treatment working to fight the cancer but it has been hard. Yesterday I finally got these problems under control. worst: [adverb] to the extreme degree of badness or inferiority. Sorry to be such a negative misery , I am usually upbeat and positive but wanted to ask if these cycles compound with the side effects as I am not sure I could cope with another 2 cycles. A total of 1,306 newly diagnosed patients were randomized in a 1:1 ratio to receive 600 mg of NUBEQA twice a day or matching placebo, plus ADT and 75mg/m 2 of docetaxel, for 6 cycles. I think knowing that you only have one more after that is where you find the strength to continue. They all worked with the FEC but this new chemo is so much harsher on my mouth. I was diagnosed with grade 3 breast cancer in may. She is on this dose denseShe is on this dose dense regiment; every two weeks; 4 rounds of AC followed by 4 rounds of Taxol (and I think it's five day after Nuelasta shots). Thanks for being such a grand support for her. (Sarcoma, Soft Tissue Sarcoma, Stage 3, Undifferentiated Pleomorphic Sarcoma [UPS]). I have just had 4 cycles of FEC and other than the 3rd one, coped OK and carried on working a combination of at home and in work on my good week. I know it is really hard to go back when you know how rough it will make you feel-I tried to look at as a bad dose of flu( a normal person problem)No one would expect you to get out of bed with flu. Best wishes for continued good health. Carry on being her strength and pass on my love to her xx. Thank you for sharing your journey and giving me hope. xx. You have given me some great pointers and hopefully I can be calmer about my next 2 cycles. I am hopeful that the next two cycles will be less of a shock to the system. I would have Gemcitabine on week one. I am sorry that she is not feeling well. Fellow sufferers, keep your hopes up. Talk to your care team about these recommendations. Make sure she is getting alot of water, eat fruits and vegetables. Peripheral neuropathy is a toxicity that affects the nerves. Take regular Paracetamol and Ibruprofen all day every day. At least with experiencing this cycle we will be more prepared. It was just the drugs working their way through my system. If docetaxel does not work or stops working, cabazitaxel (Jevtana) may . Copyright @ 2019 binews.org | All Right Reserved. If youre suffering from epiphora because of this medication, you might consider a Taxotere lawsuit. I was diagnosed in Feb 2013 and had a rt mastectomy op in March. You should not drive after the infusion until you know how it will affect you. I ended up in hospital with spiked temperature, although nothing showing in my bloods, but tremendous discomfort and feeling very unwell. Your physician will order lab tests throughout your treatment to keep an eye on your levels. One of the most major Taxotere side effects is epiphora or, in simple terms, watery eyes. If the platelet count becomes too low, you may receive a transfusion of platelets. Chemotherapy drugs can deplete your supply of red blood cells, the cells that carry oxygen throughout your body. I often feel like it's too much and want to give in. She is also tired of taking pills. Health Advice: What Is A CPAP Machine And How Does It Work? TAXOTERE (docetaxel) Injection Concentrate is a clear yellow to brownish-yellow viscous solution. Ask your oncology care team before scheduling dental appointments or procedures. And the near close is Sunday because it's Sunday and it has always been pretty precious. I haven't had much information about that yet. She did have both extremes of the intestinal issues. Today it was announced that his name would be on a car at Le Mans. By the second cycle,my nausea would start as Im getting my infusion. So she then got a lumpectomy. I will speak to nurses but most of what I am going through is normal side effects for the Docetaxel chemo. But then again what do I know? Signs of a reaction can include: feeling hot or flushed shivering itching a skin rash feeling dizzy a headache feeling breathless or wheezy swelling of your face or mouth pain in your back, tummy or chest. Docetaxel is given by intravenous (IV, into a vein) infusion, usually over an hour. : those who have a cold, fever or cough or live with someone with these symptoms). worst daysfor me it was the week after the infusion..I just fall apart.tired, ache, intestinal issuesetc. So into hospital she went each time. I know the taste thing lasts for a while but I crave something good to eat. Wear sunscreen (at least SPF 15) every day, wear sunglasses and long sleeves/pants to protect your skin. I was diagnosed in August with Breast cancer. I spent a week in hospital after the 3rd Taxotere + radiotherapy. On 9-1-09, I finished 6 cycles of Taxotere, Carboplatin and Herceptin. Except she would always end up in hospital as her temp would spike along with the joint pains. Know that you are two thirds of the way there. Meanwhile just keep in mind that you are going through this because you want to live and enjoy your family. Its often very difficult to treat edema caused by cancer and chemotherapy. Liked the clearer head but found days 3 to 6 the worst when ankles, knees or hips gave way. My tumour is responding well as confirmed by a recent MRI between cycle 3 and 4 so I need to continue to hopefully get through these last two cycles. No cancer cells were found, and she was deemed "no evidence of disease". I don't think you have "gone wrong" anywhere, more that T has hit you hard and you would like to be in a better place for the next 2. APAP vs. CPAP: Whats the Best Machine for Sleep Apnea? 4 days after having it I was so sick I could not go to work. Even if it is to moan. I mentioned this thread to her - the common wisdom that the first is the worst because of the uncertainty and the rest is more of the same, only more so. TAXOTERE was first approved for the F.D.A. Best of luck to you all xxx, I would be happy to receive news and updates from Cancer Chat, NICE suspected cancer referral guidelines, Cancer Research UK for Children & Young People. This may vary depending on whether the number of blood cells has returned to normal between each cycle. Drank gallons of water to try and flush it out. I've had all three FEC sessions and coped really well and was positive and active. You should not breastfeed while receiving this medication or for 1 week after your last dose. But I'm on SSP and we can't afford to have him stay at home every time I feel ****. Hi. Did they check your bloods in A&E?? Docetaxel can pass into body fluids (urine, feces, vomit). Today is the first day of actually feeling better after first cycle of Docetaxel, I am going to enjoy this last week before the next cycle of chemo starts. It was a one-and-a-half-hour dose. Take care and we will get through this. The problem some people run into with Taxotere is that the hair loss can sometimes be permanent. What Is the Taxotere Mechanism of Action? It's important to take things day by day. I asked my Oncologist if there was any alternative as the side effects are so awful, but there isn't. If red meat is a problem, eat chicken, turkey, eggs, dairy products, and fish without a strong smell. You won't be up to doing anything. I think I am coming to the end of feeling like I have hit by a bus with the chronic aches in all my joints and bones. an infection was never found, though. Also, try eating low-fiber, bland foods, such as white rice and boiled or baked chicken. For at least 48 hours after you receive a dose, avoid allowing your body fluids to come into contact with your hands or other surfaces. TAXOTERE (docetaxel) injection, for intravenous use . I had terrible diarrhoea because of neutropenia and had 5 days of IV antibiotics. Its common to lose hair when youre undergoing cancer treatments. Perseverance!! Even when carefully and correctly administered by trained personnel, this drug may cause a feeling of burning and pain. The taste improved just before the next treatment. It helps with pain so uncomfortable in spasms but endurable if I dont climb too many stairs with lead legs, It may have helped the mouth too, the stronger dose did make me reach for the bonjella where moments before was ok. 10 days of horrible tastes and softer foods has been hard. Thank you for the support, hope you are doing well. It wasnt until the following year that food started to taste good again. So far I have been ok on the 2nd cycle just starting to feel the side effects kicking in this evening . Get the latest cancer stories, helpful resources, and personalized advice directly to your inbox. I end up with wet pillows at nightnever had that with Tamaxifen or in 50s. The ResMed machine is a medical device used to treat sleep apnea, a condition that causes pauses in breathing during Obstructive sleep apnea is a sleep condition in which a person's airway is obstructed during sleep, resulting in shallow breathing Dry eye is a common condition that can range from minor irritation to severe discomfort. Taxotere is a part of many peoples cancer journey. Of course, we each respond as individuals. The interval between each treatment gives your body time to recover. Pass into body fluids ( urine, feces, vomit ) intended ) close, mine starts next Tuesday (. Dark, brittle or fall off that she is not feeling well on car. 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